Ben Greenfield Fitness: Diet, Fat Loss and Performance

396: The Myth About Antioxidants Blunting Exercise Response, Does Red Meat Really Give You Cancer, How To Make Coffee Healthier, Are Pre-Workout Supplements Addictive? (& The Brand New Ben Greenfield Podcast Co-Host Revealed!)

Q&A Episode 396 Have a podcast question for Ben? Click the button at the bottom of the page (or go to SpeakPipe), or use the Contact button in the free Ben Greenfield Fitness app. Click here for some tips on how to have the best chance of having your question featured on the show! News Flashes [9:00] The new podcast host Jay Wiles's website The latest "red meat gives you cancer study" show only a RELATIVE risk increase from 0.5% to 0.6%...AND only with processed meat. Read headlines and studies carefully folks: https://academic.oup.com/ije/advance-article/doi/10.1093/ije/dyz064/5470096?searchresult=1 This paper is freakin' awesome. How humans adapt to stressors such as cold, altitude and diving: http://www.nielsenlab.org/wp-content/uploads/2018/08/1-s2.0-S0959437X18300777-main.pdf Biohackers are implanting everything from magnets to sex toys: https://www.bloomberg.com/news/articles/2018-10-19/biohackers-are-implanting-everything-from-magnets-to-sex-toys You can receive these News Flashes (and more) every single day, if you follow Ben on Twitter.com/BenGreenfield, Instagram.com/BenGreenfieldFitness, Facebook.com/BGFitness, BenGreenfieldFitness.com/Snapchat, and Google+. Special Announcements [28:30] -Click here to follow Ben on Snapchat , and get ready for some epic stories about his morning, day and evening routine!  Ben's Adventures: [28:30] - May 29, 2019: Community Talk on Stem Cell Procedure, Charleston, South Carolina. Sign up for an exclusive, semi-private event featuring myself and Dr. Craig Koniver of Koniver Wellness. The lively discussion will take place at Tradd's downtown over dinner in a private room for 80 guests. Sign up here! - June 6, 2019: An Afternoon of Transformation with Ben Greenfield, Denver, Colorado. A special event hosted by MaxLiving, which exists to transform lives through chiropractic. - June 15, 2019: Ultimate Fitness Run, Mt. Spokane, Washington. Join me and my family for a fun, as-competitive-as-you-make-it day outside for an OCR-style challenge. Register here while you still can. This event sells out quickly each year. Save with code: BEN10UFR and register here. - June 23 - July 7, 2019: European Detox Retreat, Paracelsus al Ronc, Switzerland. At this 2019 liver detox and R&R retreat at the beautiful Swiss Mountain Clinic in the Italian quarter of Switzerland, you'll stay on-site and receive diagnostics and treatments from the best doctors of biological medicine to detox your liver and your soul. Here's the link to more info. - August 3, 2019: Spartan Sprint at the LA Stadium, Los Angeles, California. It's Rally Time, Los Angeles. The Big A. Angel Stadium. Whatever you call it, this place is legendary. Now, Spartan is headed to this historic ballpark for an epic Stadion course. Get ready to take on 3 miles and 20 obstacles through nearly every part of the stadium. Sign up here! - September 27 - 29, 2019: Spartan World Championships, Squaw Valley, California. Right beside Lake Tahoe, this epic venue was once host to the 1960 Olympic Winter Games. Join me there for the greatest obstacle course race in North Tahoe Lake, Olympic Village, CA. Sign up here. Sign up here! -View Ben's Calendar Here Click here for the full written transcript of this podcast episode. This podcast is brought to you by: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -JOOVV: After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. Order using my link and receive a nice bonus gift with your order! -ButcherBox: Delivers healthy 100% grass-fed and finished beef, free-range organic chicken, and heritage breed pork directly to your door on a monthly basis. All their products are humanely raised and NEVER given antibiotics or hormones. New subscribers will receive 2 LBS of FREE wild caught Alaskan salmon + $20 OFF their first box by going to butcherbox.com/ben -Zip Recruiter: As your qualified candidates roll in, we make it easy to screen & rate them, allowing you to make the best hiring decisions for your business. Try it for free when you use my link! Listener Q&A: Should You Eat Black Ant Extract? [37:20] Sartell says: I recently purchased the polyrhachis ant supplement. I took it prior to a workout and I felt an analgesic effect. I've had many shoulder surgeries, and I felt a lot better when I took this. I did some more research and saw it is touted as having anti-inflammatory and anti-oxidant effects. I know that antioxidants can blunt the hormetic effect of exercise. So should I be worried about that with this supplement? In my response, I recommend: -Black Ant Extract from Lost Empire Herbs -My podcast on hydrogen rich water -Thorne Quercetin phytosome -Organic green tea polyphenol -Blood flow restriction straps (BFR Bands) -Study: Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve How To Keep Coffee From Giving You Adrenal Fatigue [59:40] Unknown says: I'm a big fan of coffee, and excellent coffee at that. I have a concern that I am stressing my adrenals constantly. What do you suggest on how to enjoy my coffee and keep my adrenals in good shape, or am I worried for no reason? In my response, I recommend: -Organic decaf coffee -Thorne Theanine -Four Sigmatic Reishi -MiCacao -DandyTea -Tulsi (holy basil) extract -American Nutraceuticals Whole Foods Vitamin C -Jigsaw Vitamin C + Lysine -Colima Sea Salt -Organic Ceylon Cinnamon Are Pre-Workout Supplements Addictive? [1:13:15] Unknown says: What's your take on pre-workout supplements? I assume the answer has to do with what kind of exercise the person is doing and what he/she is trying to achieve. Do you recommend pre-workout supplements? Will my body become addicted to the extra "boost" meaning if I don't take the supplement, I'll feel weaker and slower? In my response, I recommend: -NuCalm -Halo -Biotropic Lab supplements  -Essential amino acids (Kion Aminos) -Wim Hof Breathwork -Brad Kearn's article on BGF about cold thermogenesis pre-workout Giveaways & Goodies [1:20:15] -This week's top iTunes review - gets some BG Fitness swag straight from Ben - click here to leave your review for a chance to win some! ------------------------------------------ Prior to asking your question, do a search in the upper right-hand corner of this website for the keywords associated with your question. Many of the questions we receive have already been answered here at Ben Greenfield Fitness! -----------------------------------------------------

Ben Greenfield Fitness: Diet, Fat Loss and Performance
01:24:36 5/8/2019

Past Episodes

Peak: The New Science of Athletic Performance That is Revolutionizing Sports is a new book, by my fellow C-ISSN and CSCS Dr. Marc Bubbs. It was one of my best reads of the year for all things sports science. A few of my big takeaways include: - Endurance athletes seem to need more sleep than strength athletes, and both seriously suffer when sleep is anything less than 6 hours. - A temperature change in your fingertips is likely the first circadian cue you get at the beginning of the day (I could totally see a potential jet lag device that warms the fingers - I'll take the royalty for that, please. ;) ). - Aerobic training for strength athletes could assist with their immune system strength. - Loading with probiotics for 2 weeks leading up to competition could give you an ergogenic edge. - Elite athletes on a subpar diet show the same blood biomarkers as those with pre-diabetes and a fructosamine blood test can be one of the best ways to measure this. - Top supplements proven to work in exercise science, with the strongest track history, are creatine, caffeine, nitrate precursors (e.g. beet), whey protein, beta-alanine, and sodium bicarbonate. - Athletes with the CC genotype of the CYP1A2 gene are actually hampered in performance in response to caffeine intake. - Eating carbs too far from a performance event (e.g. 60-75 minutes) results in hypoglycemia before the event vs. consuming them closer to the event (e.g. 20-45 minutes) - Fish oil can stimulate muscle building by stimulating mTOR pathways. Vitamin D and creatine are also very good for recovery, not just performance. Creatine can even be helpful for TBI/concussions. - High sugar intake is associated with lower heart rate variability (HRV). - Cold water immersion (CWI) beats cryotherapy for recovery, hands down. You can get this brand new book here. But I also decided to get author Dr. Marc Bubbs on this podcast to take a deeper dive into he concepts above, and many others. He is a licensed Naturopathic Doctor, Performance Nutrition Lead for Canada Basketball Team, Speaker, and former Strength Coach. Marc also hosts the Dr. Bubbs Performance Podcast, connecting listeners with world-leading experts in human performance and health. Dr. Bubbs regularly presents at health, fitness and medical conferences across North America, UK and Europe and consults with professional teams in the NBA, NHL, and MLB teams. He practices in both Toronto, Canada and London, England. During our discussion, you'll discover: -How Marc gathers, curates and assimilates new information for his practice...8:45 Struggled as a young athlete with disease, etc. and discovered naturopathic medicine He realized that there wasn't much of a market for it (circa 2000) but he embraced it and became the best at it The more personal contact with the source of info, the better (there's nuance in conversation that doesn't make it into an academic paper) Vast resources available on the Internet (and they're all true, of course) -Current research on caffeine as an ergogenic aid...15:00 Study conducted by Nanci Guest, University of Toronto: Cycling time trial under 3 different conditions: 0 caffeine 2 mg caffeine 4 mg per kg of caffeine AC gene variants had no benefit AA gene variants had benefit at both 2 mg and 4 mg levels Athletes with the CC genotype of the CYP1A2 gene are actually hampered in performance in response to caffeine intake The sweet spot: 3-6 mg of caffeine per kg per day 23 and Me test will identify CYP 1A2 gene -How endurance and strength athletes differ regarding sleep needs...21:18 Endurance athletes fare better on the upper end of the sleep suggested amounts (8-10 hrs) They also suffer more on lack of sleep Greater volume of training More early morning sessions Sleep is #1 recovery tool some docs recommend It's one thing to acknowledge the need, quite another to actually get more sleep -The relationship between finger temperature and circadian rhythm...31:25 Fingertips are the first to sense changes in environment Possibility of warming hands to help body adjust its circadian rhythm while traveling ChiliPad Ben sleeps on -How aerobic training can help the immune system of endurance athletes... "Elite performance is incompatible with frequent illness." --Dr. Michael Gleason Maintaining an aerobic base supports innate immunity Aerobic training in the protocol of a strength athlete will improve immune system Consider incorporating aerobics if red flags of sickness or fatigue occur Could be a means of recovery Simply being well enough to train is a big part of the picture Don't forget fundamentals like washing hands Fingertips, webs and backs of hands are often missed -Probiotics as an ergogenic and performance enhancing tool...42:10 Study on Olympic athletes in 2008: 2/3 of those studied showed benefit in 2 key areas: Preventing upper respiratory tract infection Reversing upper respiratory tract infection Start 2 weeks before event Colostrum can be efficacious while performing in the heat Gut is a "black box" of the body; a key indicator in assessing overall health -Up and coming supplement research and diet strategies Marc is following...50:45 "Food first" approach Creatine, whey protein, caffeine are major players Nitrate precursors: beet root, arugula Endurance sports, struggle to lose weight: have the wrong approach Nicotinamide riboside Ketones for concussion recovery High rate of head trauma among teens Women's ice hockey is the highest risk Peptides -Why athletes on a subpar diet show the same blood biomarkers as those with pre-diabetes...56:10 Endurance athletes are more concerned with hypoglycemia, not hyperglycemia Study: 4 of 10 participants spend 70% of the time with blood glucose in pre-diabetic range Exercise is a stressor; contributes to raising blood glucose Over fueling more of a problem than we think Case study in Japan on two ultra-marathoners: one elite, the other sub-elite on a 100 mile race At wake-up: elite has glucose level of 90; sub-elite is 110 Sub-elite glucose level rises, then crashes around mile 70 Elite runner came through just fine Fructosamine measurements for blood glucose levels HA1c skews to more recent fueling in its readings 2-3 week window vs. 3 month on HA1c Measuring glycated albumin rather than glycated hemoglobin More expensive; used for a more acute picture -The best time to consume carbs before training...1:07:45 Dr. Mark Russell: Half-Time Strategies to Enhance Second-Half Performance in Team-Sports Players Biggest drops in glucose came from those who had drinks 75 minutes before the game Emma Stevenson of Newcastle University did a study on maltodextrin vs. honey Maltodextrin had blood sugar drop of 19% Honey had blood sugar drop of 4% Time carb intake so that blood glucose spike takes place during the event Optimal overall carb intake for strength vs. endurance athletes: Strength: 4-7 g per kg per day Endurance: 6-10 g per kg "Training low" in team sports: low carb availability -Comparing the effectiveness of cold water immersion (CWI) to cryotherapy...1:22:40 -And much more... Resources from this episode: -Peak: The New Science of Athletic Performance That is Revolutionizing Sports -Examine Research Digest -Alan Aragon's Research Review -Chilipad Ben sleeps on -The combo of ATP and HMB Ben mentions -Dr. Mark Russell: Half-Time Strategies to Enhance Second-Half Performance in Team-Sports Players Episode sponsors: -Kion Aminos: Building blocks for muscle recovery, reduced cravings, better cognition, immunity, and more. Get 10% off your order of Kion Aminos, and everything at the Kion site when you use discount code: "BGF10". -JOOVV: After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. Order using my link and receive a nice bonus gift with your order! -Thrive Market: Organic brands you love, for less. Your favorite organic food and products. Fast and free shipping to your doorstep. Receive 25% off your order when you use my link! -Birdwell Beach Britches: Quality is our Gimmick isn't just our slogan, it's a commitment we honor with every stitch we sew. 100% money back guarantee. Get 10% off your order, PLUS free shipping on any order over $99 when you use discount code: BENG. Do you have questions, thoughts or feedback for Dr. Bubbs or me? Leave your comments below and one of us will reply!  
01:32:54 6/21/2019
This audio/video overview by Dr. Ally Perlina of Viome goes in depth on Ben's latest gut microbiome results from Viome. In this episode, you'll learn how to customize your diet and lifestyle based on the genetics of your gut. Dr. Perlina is the Chief Translational Science Officer at Viome. She leads the Viome team on the development of actionable pathway analytics, functional microbiome profiling, and integration of Viome test results into food and supplement recommendation logic. Ally came to Viome from working with Dr. Craig Venter at Human Longevity, Inc. She brings over 17 years of industry experience, which include Thomson Reuters, Quest Diagnostics, and several startup organizations where she led R&D groups, scientific product development efforts, and translated knowledge and insights from clinical data analyses into actionable results. S he's a world-class expert in pathway analysis and translational systems biology, which are critical in addressing the complexities of health and disease from different data types in a meaningful holistic way. This cross-functional perspective and passion for making scientifically powered precision medicine insights actionable and scalable has been Ally's driving force ever since she was investigating gene expression correlates of brain tumors and patient drug response at UCLA while getting her doctorate training in Human Genetics. Ally's ability to "translate" the signals from genomics, transcriptomics, metabolomics, etc., into something valuable for human health today allows her to lead a diverse team of scientific, clinical, and nutritional experts that together with data science make truly personalized Viome recommendations with molecular-level precision To learn more about Viome and what it is, you can click here or check out these previous resources I've created on this cutting-edge way to test all the bacteria in your gut, along with the postbiotics they produce: - Article: What Is Viome? How Gut Metatranscriptome & Microbiome Analysis Can Change Your Health  - Podcast: Age Reversing Via The Gut, The Ultimate Anti-Anxiety Pill, Customized Probiotics & More With Billionaire Entrepreneur & Viome Founder Naveen Jain - Podcast: Poop, Bacteria & You: The Latest Cutting-Edge Science Of The Human Microbiome (& How To Affordably Test Your Own Gut) - Podcast: The Ultimate Guide To Self-Quantification - How To Test, Track & Interpret Blood, Saliva, Urine, Hair & Poop During this audio/video, you'll discover: -Ben's GI summary...7:23 Most important themes to address are several specific functions dealing with digestive efficiency Active microbes: There are 134 active microbial species detected in the sample, which means that Richness is within the average range but may need improvement. No active Eukaryotes were detected There are 2 active plant viruses: Prunus necrotic ringspot Pepper mild mottle -Overall microbial richness...9:50 Ben's score is 134 out of 400; average score (5-95 percentile) The microbial could use a boost, but nothing too alarming Recommended foods: Sauerkraut enriches and diversifies the microbiome Walnuts increase microbial diversity Olive oil contains MUFAs, which are a group of fatty acids; weight management, increases bacterial diversity, decreases inflammation Recommended supplements: Probiotics Polyresveratrol and cranberry containing supplements -Metabolic fitness score...18:35 Ben's score is GOOD, in the 18th percentile of the Viome population (improved from Sep. 2018) -Inflammatory activity...21:10 Ben's overall score is AVERAGE LPS biosynthesis pathways: average Methane gas production pathways: needs improvement Sulfide gas production pathways: needs improvement Flagella assembly pathways: average Biofilm, chemotaxis, virulence pathways: average Balance is the goal, not optimal scores in every area Although the score is "average" it's on the higher end of the spectrum -Proinflammatory microbial activity, and active pro inflammatory pathways that indicate potential GI inflammation...32:40 -Butyrate production pathways and active butyrate producers...45:45 Ben's overall score is GOOD Butyrate is good for metabolic fitness Regulates satiety, good for insulin sensitivity Goes hand in hand with inflammation scores Butyrate is a short chain fatty acid (SCFA); associated with beneficial functions for the host Resistant starches and fibers: resist the digestive system of the host -SCFA production pathways and active SCFA producing microbes...51:40 In addition to butyrate: acetate, acetyl phosphate Active probiotic in Ben's sample Many different pathways that lead to butyrate production -Recommendations for Ben's diet...55:23 Bone broth (mammal) Oregano Jicama Turmeric Phytometabolizing microbes and active pathways: Red, blue and blackberries Riboflavins -Digestive efficiency...59:20 Ben's overall score is AVERAGE Protein fermentation: needs improvement Gas production: needs improvement Methane gas production pathways: needs improvement Sulfide gas production pathways: needs improvement Putrescine production pathways: needs improvement Butyrate production pathways: good Salt stress pathways: good Protein fermenters and active protein fermentation pathways Omithine Putrescine Cadaverine Ammonia Urea Recommendations related to protein fermentation: Mung bean sprouts Fennel bulb Alfalfa sprouts Grapefruit -Hydrogen sulfide production pathways and hydrogen sulfide producing microbes...1:15:50 Exacerbated by certain foods Disruptive to the gut lining Proinflammatory if produced in excess Sulfate (or sulfite) is deleterious Recommendations specific to microbial gas production, particularly hydrogen sulfide: Broccoli Brussels sprouts -Vitamins produced by the gut microbes and detox of the microbiome... -And much more... Resources mentioned: -Viome Episode sponsors: -Kion: My personal playground for new supplement formulations, Kion blends ancestral wisdom with modern science. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -Four Sigmatic: I've been using Four Sigmatic products for awhile now and I'm impressed by the efficacies of their mushroom products. I use them. I like them. I support the mission! Receive 15% off your Four Sigmatic purchase when you use discount code: BENGREENFIELD -Clearlight Saunas: You can be sure that I researched all the saunas before I bought mine and Clearlight was the one that stood out from all the rest because of their EMF and ELF Shielding and their Lifetime Warranty. Use discount code: BENGREENFIELD to get $500 off your sauna and a free bonus gift! -Zip Recruiter: As your qualified candidates roll in, we make it easy to screen & rate them, allowing you to make the best hiring decisions for your business. Try it for free when you use my link! Do you have questions, thoughts or feedback for Dr. Ally or me? Leave your comments below and one of us will reply!  
01:41:54 6/19/2019
I'm constantly playing and experimenting with new devices and so-called biohacks to enhance sleep and cognition. One of my favorites of late is a very handy device called the NuCalm, which I've been using to simulate an entire 120 minute sleep cycle with just a 20 minute daily powernap. The NuCalm is a next-level cranial electrotherapy stimulation device that uses both a relaxation cream and mild stimulation to help your brain interrupt the adrenaline and cortisol release by mimicking what naturally occurs in your brain right before you sleep. It includes an app with "music" - which is actually neuroacoustic software that delivers frequencies to your brain which take you down to theta brain wavelength. This thing lets me get a 20-minute intense period of relaxation even when I can't nap, and I'm now ducking away and using it nearly every day, particularly during travel and on airplanes. It's spendy, but in my opinion, well worth it. You can get a NuCalm here and save $500 with code: BEN500. My guest on this show is Jim Poole Chairman, President and CEO of Solace Lifesciences, Inc., the maker of NuCalm. J im is an accomplished business executive with extensive experience in the healthcare,. biotechnology, dental, market research, and IT industries. Mr. Poole manages the strategic direction and ongoing operations of Solace Lifesciences, Inc., a neuroscience company focused on personalized wellness and performance. In 2015, Solace Lifesciences, the maker of NuCalm, was granted the world's sole patent for "Systems and Methods for Balancing and Maintaining the Health of the Human Autonomic Nervous System." Mr. Poole has successfully launched global products, managed growth strategies, and effectively optimized business operations for large and small organizations alike. Prior to joining Solace Lifesciences, Jim co-founded Focused Evolution, a premier global management strategy-consulting firm. As a Managing Partner, he managed mergers and acquisitions, due diligence, and growth strategies for venture capital and private equity firms. Under Jim's leadership, Focused Evolution grew into a multi-million dollar consulting firm, serving a global client portfolio of 49 companies, across a broad in a range of industries. Jim serves on the board of directors of several medical device firms around the world. He is a recognized business leader, public speaker, an accomplished author, and has published numerous articles in industry trade journals and lectures all over the world globally on topics including stress, recovery, performance, and business strategy. Jim has published over 30 articles in industry trade journals. A New York state native, Poole earned a BA in psychology from the University of Massachusetts at Amherst and an MBA in International Business & Marketing from Babson College. During our discussion, you'll discover: -What exactly is a NuCalm?...8:30 Cranial electrotherapy stimulation (CES) Designed to halt the stress response and raise the parasympathetic response Was developed over the course of 20 years by a neuroscientist/quantum physicist/naturopath, Dr. Holloway He's not myopic: you'll find biochemistry, electrical signaling Physiological benefit of living like a monk The hand-held device is the core of the product Brain and body communicate in 2 ways: chemical and electrical messaging Cycles brain wave function into data Key is in controlling the adrenal glands It's FDA cleared to treat insomnia, anxiety, depression Amino acid GABA (gamma-Aminobutyric acid0); the antithesis of adrenal stimulation GABA is transmitted to the brain via the cream Shuts down the HPA axis (adrenals) The cream contains, in addition to GABA, taurine, glycine, casein tryptic hydrolysate (the protein found in mother's milk) If you didn't get all that, get this: The device relaxes the nervous system, which allows the GABA in the cream to reach the brain and work its magic -How the audio features in the NuCalm app enhance the user experience...22:20 Binaural beats: Discovered in 1839 The ear can't hear them; they bring the signal into the brain Binaural signal processing (512 hz into the left ear; 500 hz into the right ear) Reticular activating system: Stimulation filter to the brain Two functions: pattern recognition and find a shortcut One track on the NuCalm app is over 700 mb of data (compared to 5-6 mb on an iTunes track) Non-linear oscillating algorithm: Takes the brain from beta (awake) to alpha and theta Theta is when the cells cleanup and create energy source for themselves (healing zone) -The science behind going through an entire sleep cycle in a 20 minute power nap...28:00 NuCalm's claims attracted top scientists to validate them World's preeminent expert in HRV verified that the NuCalm truncates a 2 hours of sleep into 20 minutes Won "best of CES" at Consumer Electronics Show Dr. Hollowell was resistant to creating a 20 minute track mimicking an entire sleep cycle (was 40-50 minutes) Supply followed demand; after months of research the 20 minute track was a reality -How the NuCalm device measures heart-rate variability...37:40 Low frequency (LF) pertains sympathetic nervous system High frequency (HF) the parasympathetic Monk-like meditation level within one minute Took 5 years to secure a patent on the technology Worked with the most renowned experts on HRV C.K. Peng Captured date from 2 groups: metastatic stage 4 cancer, professional athletes LF is lowered while raising the HF 100 patients with depression and anxiety were studied with astounding results after using the device We understand intuitively that stress causes disease, but don't understand why We can't understand the intangible Long-term time horizons make us apathetic in our youth High-stress/poor sleep lifestyle = not enough time in theta or the 2nd stage of sleep Cancer is the best way to articulate the breakdown We all have cancer in our bodies, however our immune system kills them when it's functioning properly Stress breaks down this function over time Physiological benefit: It activates the vagus nerve Slows breath down to one breath per 10 seconds Syncs heart with the lungs Fully oxygenated -How the NuCalm affects recovery...47:55 Elite military units use the device for expedited recovery without the use of drugs It takes the foot off the accelerator, in a manner of speaking Return on investment: 30 minutes yields 12-15 hours of highly focused work Autonomic system is key to managing stress, anxiety, fear, etc. The itty bitty shitty subcommittee in the back of your brain goes away Without proper sleep, we literally stress ourselves to death The offer is not to cure or heal anything; it's to alleviate stress and allow the body to heal itself, the immune system to fight disease Even monks love the device -The NuCalm's effect on the nervous system beyond HRV and the vagus nerve...56:30 24 page study  -How the NuCalm affects (or interrupts) your normal sleep schedule...1:01:05 Don't take the power nap close to normal bedtime 15 minute rule: use it as an aid to fall back asleep in the middle of the night Sweet spot: between 1-4 pm (normal time body wants to take a nap) Your body cannot compensate for sleep debt NuCalm is not a "hack" for getting less sleep If you live 100 years, you should sleep for 33 years You stay in theta during the NuCalm power nap (which is where the body heals itself); ordinarily you'll be in delta The body relies on GABA during sleep The body keeps the nutrients it needs; secretes what it doesn't The GABA in the cream during a mid-day power nap will still be there when you go to bed at night -Final rapid-fire questions...1:10:45  Whether there is any efficacy in increasing the cranial electrical stimulation using the device About the other settings on the device (relaxation and recovery) About the Ignite app [link] (sympathetic stimulation) Opposite effect of the NuCalm Can be used in tandem, but not independently of NuCalm -And much more... Resources from this episode: -NuCalm: The NuCalm is a next-level cranial electrotherapy stimulation device that uses both a cream and mild stimulation to help your brain interrupt the adrenaline and cortisol release by mimicking what naturally occurs in your brain right before you sleep. It includes an app with "music" - which is actually neuroacoustic software that delivers frequencies to your brain which take you down to theta brain wavelength. This thing lets me get a 20-minute intense period of relaxation even when I can't nap, and I'm now ducking away and using it nearly every day, particularly during travel and on airplanes. It's spendy, but in my opinion, well worth it. You can get it here and save $500 with code: BEN500. - The Fisher Wallace Circadia Ben mentions early in the interview -The other apps Ben mentions: Sleepstream Pzizz Brain.FM -Ecomeditation .mp3 for simulating sleep -Yoga Nidra for sleep Episode sponsors: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -Organifi Green Juice: Now you can get all your healthy superfoods in one glass...with No Shopping, No Blending, No Juicing, and No Cleanup. Get a 20% discount on your entire order when you use discount code: BENG20 -Pique Tea: Achieve your health goals easier and faster with Pique Tea. My mental clarity is through the roof and energy levels have never been better since I've been drinking Pique Tea. Get 15% off your entire order when you use code: GREENFIELD -Gluten Guardian: Are you ready for upgraded digestion? Take your body to the ultimate edge of human potential and become biologically optimized with Gluten Guardian. Save an additional 10% off your entire order when you use discount code: GREENFIELD Do you have questions, thoughts or feedback for Jim or me? Leave your comments below and one of us will reply!
01:26:33 6/14/2019
I'm constantly blown away by the amount of genetic data and actionable information one can garner from a simple bit of saliva. In today's episode, you're going to get an insider glimpse into how to go way beyond something as simple as 23AndMe or Ancestry and instead learn how to get truly useful health information that you can use to enhance health, performance, sleep, gut function, neurotransmitters and cognition and much more. My guest on this podcast, Dr. Mansoor Mohammed, has an extremely impressive background in the field of genetics. His credentials include: -BSc. Specialized Honours in Molecular Genetics | University of Guelph | Guelph -Doctor of Philosophy with Distinction in Molecular Genetics & Immunology | University of Guelph | Guelph -Postdoctoral Clinical Cytogenetics Fellowship | University of California | Los Angeles -Postdoctoral Clinical Cytogenetics Fellowship | Baylor College of Medicine | Houston Dr. Mansoor is now the President and CSO of The DNA Company, a leading and innovative provider of comprehensive Functional Genomics testing and consulting and an industry first: individually customized supplements based on your genetics. He is widely regarded as a pioneer in medical genomics and has been the recipient of multiple academic and industry awards. He is the holder of several patents in the general fields of molecular diagnostics and genomics research and is one of the most sought-after national and international conference speakers in the genre of personalized medicine. Prior to his role at The DNA Company, Dr. Mansoor was: - Founder and President of ManaGene (2010-2018) - CEO of Combimatrix (Nasdaq traded leader in diagnostic genomic microarrays) (2006-2010) - Director of Genomics at Quest Diagnostics (The world's largest reference laboratory with a market capitalization of over $10 billion US) (2003-2006) - Director of Research and Development at Spectral Genomics (one of the industry's first commercial genomic microarray developers spun out of Baylor College of Medicine under Dr. Mansoor's scientific leadership) Dr. Mansoor maintains an active clinical practice as a genomics consultant to some of the leading executive health clinics in Canada and abroad. During our discussion, you'll discover: -What makes each DNA test different and how to choose what's right for you...9:30 Consider the various elements of genetic testing: SNPs (pronounce "snips"; single nucleotide polymorphisms) Copy number variation (CNV) INDEL (insertion/deletion polymorphism) Understand how the various labs go about testing the elements Humans have two identical copies of the DNA code (from each parent) When testing for SNPs, the genetic paragraph is "read" and looks for variations between the two The more paragraphs you try to query simultaneously, the greater risk of error (false negatives/positives) Characteristics of a proper DNA test: Concern is for the physical manifestation of the genes, not the genes themselves Cellular function is key indicator Identify the genes that influence the desired outcome Pinpoint the specific DNA to test vs. "shotgun" approach Avoid drawing data for data's sake -A review of Ben's DNA test and how they compare to his two sons...25:00 Two different reports: Genome Pulse Report and Hormone Pulse Report (looking at the GPR) Vascular function Cells that line the vascular system receive the most wear and tear 9P21 markers (not genes) are correlated with the lining of the blood vessels; "the heart of the human genome" A alleles and G alleles The more G alleles you have, the less resilient is the endothelial lining Increase good quality vegetable matter People with multiple G alleles benefit less from vegetable matter (like red wine) than those with none Smokers are more likely to die of vascular disease than lung disease Glutathione S-Transferase (GST) pathway is one of the key pathways in the body Glutathionization: the cellular process that neutralizes toxins in the body What happens when someone doesn't have 2 copies of a gene... You sometimes have genes you didn't inherit from either parent Talking about SNPs in the gene is irrelevant; As is epigenetics (alter the expression of the genes, not the genes itself) 3 vitally important GST genes: Theta 1, Pai 1, Nu1 Should a person only have 1 copy of a gene, they will produce 50% less than someone with 2 copies Ben Greenfield has 1 copy of the GSTT1 gene (as does 60% of the population) Important to not exceed a healthy toxicity threshold Ben Greenfield does not have the GSTM1 gene at all Useless to discuss SNPs for that gene The M1 gene is a backup: it can be lost with less consequence than other genes (such as the T1) What this means is that Ben Greenfield has low to average glutathione detox capacity Must be more cognizant of diet, environment, etc. Ben's two boys are missing the GSTT1 gene completely -Personalizing diet and/or supplements based on DNA test results...57:25 Youtrients [link] Nothing compares to an optimal diet (eating whole foods) Customized based on dietary limitations (lactose intolerance) Ethnic and geographic factors, as well as the environment during weaning, affect how to interpret test results Elites of Victorian era England adjusted their lifestyle (living in Scottish highlands in the autumn months) Reduce, not promote, supplementation, to where only necessary Our bodies are not designed to accommodate many of the supplements on the market "Is there a cellular function that is dysfunctional?" Then address that through supplementation More is not always better when it comes to genetics 3 disparate aspects of cellular function: Endothelial quality Detox capacity Insulin productivity and function in response to diet -Differences between the hormone pulse report and the genome pulse report...1:18:25 BDNF (brain-derived neurotropic factor) is one of the most important genes in our body First thing looking at: How does the body (male or female) convert progesterones into androgens, into estrogens t-intersection (4 points): How efficiently converting progesterone into androgens 3 things happen when you make testosterone: Use it Convert some of it into DHT Metabolize (glucuronidation) Ben has the perfect balance of the t-intersection Ben's boys are identical, except have a higher predisposed conversion of testosterone into estrogen -About the ACTN3 gene and its relation to exercise types...1:28:50 -And much more... Resources from this episode: - Click here for testing with Youtrients through the TheDNACompany. They offer their complete functional genomics test package for $399 USD (that's a savings of $50 from retail price), and your test package includes both Hormone and Genome Pulse panel tests as well as a clinical report for each panel, along with full access to their webinar series, which introduces the science and interpretation of your genomic results with regards to key biological systems and processes. Click here for that special offer from YouTrients for Ben Greenfield listeners. - Ben's Hormone Pulse results from TheDNA Company [pdf-embedder url="/wp-content/uploads/2019/06/Ben-Greenfield-HORMONE-PULSE-REPORT.pdf" title="Ben Greenfield HORMONE PULSE REPORT"] - Ben's Genome Pulse results from TheDNA Company [pdf-embedder url="/wp-content/uploads/2019/06/Ben-Greenfield-GENOME-PULSE-REPORT.pdf" title="Ben Greenfield GENOME PULSE REPORT"] Episode sponsors: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -Trusii: Contains a host of anti-inflammatory, anti-obesity, and anti-allergy benefits. For this reason, I have decided to now make consumption of hydrogen-rich water an important part of my daily nutritional routine...and I highly recommend it! Enter code: BEN at checkout and get 30% off your order! -Halo Sport: Halo Sport revolutionized physical training by being the first-ever product that can increase your neuroplasticity by putting your brain into a state that neuroscientists called hyperlearning?. The fully upgraded Halo Sport 2 was just announced and it's pre-selling for just $279 (less than half the price of the first model) when you use code: GREENFIELD. -Birdwell Beach Britches: Quality is our Gimmick isn't just our slogan, it's a commitment we honor with every stitch we sew. 100% money back guarantee. Get 10% off your order, PLUS free shipping on any order over $99 when you use discount code: BENG. Do you have questions, thoughts or feedback for Dr. Mansoor or me? Leave your comments below and one of us will reply!  
01:39:39 6/12/2019
Several months ago, I filled you in on "The 2 Best Ways To Burn Fat Fast (Without Destroying Your Hormones Or Metabolism)". But what you learned in that article only scratched the surface of the multiple mechanisms underlying why the human body can be resistant to fat loss, and how to achieve truly sustainable, long-lasting weight loss in a safe and efficient manner. So during today's solosode, you'll discover... -How fat actually gets burnt...6:20 Law of conservation of mass: Mass, in an isolated system, is neither created nor destroyed by chemical reactions or physical transformations Fat is primarily disposed of via the breath Calories, as well as excess carbs and proteins, are converted into triglycerides and stored in lipid droplets of adipocytes Excess dietary fat undergoes lipolysis, and then reesterification Triglycerides are composed of carbon, hydrogen, and oxygen Oxidation: requires inhalation of oxygen Study: When someone loses weight, where does the fat go? For 22 pounds of fat to be oxidized, 64 pounds of oxygen must be inhaled Results in 61 pounds of carbon dioxide excreted via the lungs and 24 pounds of water excreted via urine, sweat, feces, and breath Average of 17,000 breaths per day will excrete .32 lbs of carbon Sources of carbon (other than eating coal) are: dietary carbs, proteins, and fats If you didn't get all that, get this: Losing fat means consuming less carbon than you've exhaled. Even small quantities of food can foil your efforts at weight loss. The simple solution is to move more and eat less. The 16 reasons you're not burning fat the way you'd like - Chronic Inflammation...12:35 High levels of transforming growth actor beta cause irregular appetite and glucose regulation Matrix metalloproteinases (MMP): calcium-dependent zinc-containing endopeptidases Vascular endothelial growth factor (VEGF): Aids in the growth of new blood vessels; correlated with obesity Nitric oxide synthase Toll-like receptor 4 (TLR4) = meta inflammation Nos uncoupling (genetic factors) StrateGene Tree of Life, Bob Miller's site Sugar can be inflammatory but is more quickly metabolized than things like vegetable oil Chronic stress is a factor: overstimulation of the limbic system Cell Danger Response (CDR) Toxic by Neil Nathan Dr. Robert Naviaux - Glycemic variability (GV)...21:05 Refers to the blood glucose variations during the day If GV gets out of control, the body does one of two things: transfers sugar into muscles, or stores as body fat It will become fat tissue if you're not active enough throughout the day Be "ruthlessly" cognizant of blood sugar fluctuations 6 Strategies to control GV Strength training Pre-breakfast fasted cardio Book: Change Your Schedule, Change Your Life  Post-prandial walk Standing Plants, herbs, spices Ceylon cinnamon Gymnema sylvestre Berberine Apple cider vinegar Kion Lean Fiber - Cortisol and stress...30:45 Cortisol suppresses insulin secretion Measure heart rate variability (HRV) Oura Ring (Save $50 with code: GREENFIELDOURA) Podcast with building biologist Brian Hoyer Podcast Ep. 397 - Sleep deprivation...34:20 A single night of partial sleep can be deleterious Neuro endocrine effect: reduces levels of leptin; increases levels of ghrelin - Snacking and post-workout calories...35:25 "Grazing" or 6-8 small meals per day is a myth Snacking increases your GV and eliminates benefits of fasting Your body releases more growth hormone during intermittent fasting Grazing throws metabolism into sugar burning mode It takes 3 days, or 4 weeks of extreme calorie restriction for the body to down regulate metabolism The need for protein and carbs right after a workout is a myth The exception: two a day workouts - You're not moving enough...39:47 Fool your body into thinking it's in the "hunter gatherer" mode - Too much exercise...41:30 Excessive exercise, along with other stressors can lead to increased levels of cortisol and inflammation Beyond Training by Ben Greenfield Too much of the same exercise Not enough recovery days Sweet spot: 2-3 days per week, lift heavy stuff 2-3 days high-intensity interval training - Chronic cardio...43:35 Your body will catabolize muscle and store fat High-intensity cardio 2-3 days per week Reduced subcutaneous adiposity of body fat among people who follow these guidelines - The SAID Principle...46:00 Specific Adaptation to Imposed Demands Sometimes the best workout plan is the one you're not currently doing Keep the body guessing 5 modifications: Combine exercises Article "complex exercises" Active rest periods Train outside Change the center of gravity Workout at a different time of day - Lack of cold therapy...50:00 Cold is a strong metabolic stimulus Cold thermogenesis occurs when protons are forced across the inner membrane and turned into heat Beige adipose tissue Every day, 2-5 minutes cold exposure (cold shower, cold river or lake) 3x3 cold coolfatburner.com (Use code: BEN10CFB to save 10%) - Hormonal imbalance...52:25 Dutch Test Podcast w/ Jay Campbell Estrogeneration by Anthony Jay - Toxin and chemical exposure...54:40 - Food allergies and intolerances...56:30 - Micro-nutrient deficiencies... Vitamin D Chromium Biotin Thiamine Antioxidants Magnesium Boron Vitamin A Vitamin K2 Choline Genova Labs - Thyroid...59:00 - Disordered eating...1:01:01 Your body expects food at a certain time of day Results in irregular metabolism Easier to track calorie consumption when you eat the same thing, at the same time of day - Final comments...1:03:25 Everybody and every body is different It could be possible your body has reached its desired weight - And much more! Resources mentioned: - Article: When someone loses weight, where does the fat go? - StrateGene - Tree of Life, Bob Miller's site - Book: Toxic by Neil Nathan - Dr. Robert Naviaux, UCSD - Book: Change Your Schedule, Change Your Life  - Ceylon cinnamon - Gymnema Sylvestre - Berberine - Apple cider vinegar - Kion Lean - Oura Ring (Save $50 with code: GREENFIELDOURA) - Podcast with building biologist Brian Hoyer - Podcast Ep. 397 - Beyond Training by Ben Greenfield - coolfatburner.com (Use code: BEN10CFB to save 10%) - Dutch Test - Podcast w/ Jay Campbell - Estrogeneration by Anthony Jay Episode sponsors: - Kion Coaches If you are looking for a professional that can personally help you optimize your mind, body, and spirit to become the best version of yourself, and who knows exactly how I work with my own clients, just head on over to view our brand-spankin-new Coach Directory! - Organifi Green Juice: Now you can get all your healthy superfoods in one glass...with No Shopping, No Blending, No Juicing, and No Cleanup. Get a 20% discount on your entire order when you use discount code: BENG20 - ButcherBox: Delivers healthy 100% grass-fed and finished beef, free-range organic chicken, and heritage breed pork directly to your door on a monthly basis. All their products are humanely raised and NEVER given antibiotics or hormones. New subscribers will receive 2 LBS of FREE wild-caught Alaskan salmon + $20 OFF their first box by going to butcherbox.com/ben - Halo Sport: Halo Sport revolutionized physical training by being the first-ever product that can increase your neuroplasticity by putting your brain into a state that neuroscientists called hyperlearning?. The fully upgraded Halo Sport 2 was just announced and it's pre-selling for just $279 (less than half the price of the first model) when you use code: GREENFIELD Got a question for me about today's podcast? Just leave a comment below and I'll reply!  
01:06:40 6/7/2019
I recently had a chance to speak to a wonderful crowd of personal wealth management experts at the Raymond James conference in Las Vegas. During my talk, I covered both basic and advanced tactics to enhance longevity, and the talk was also recorded for your listening pleasure here. In this episode, you'll learn... -Clues from the animal kingdom about our own longevity...9:45 Lobster has high activity of the telomerase enzyme (prevents telomeres from shortening rapidly) Naked mole rat have robust protein folding mechanisms Hummingbird has extremely high metabolism; produces high amount of endogenous antioxidants which extends its life Tortoise's internal organs do not degrade as rapidly as the rest of its body The Immortal Jellyfish: Sinks to the bottom of the ocean when it dies and renews its life Humans do not tap into their longevity potential due to their deleterious lifestyle -The 12 characteristics of "Blue Zones" and how they relate to longevity... Blue Zones by Dan Buettner Air quality in your environment [17:15] We're bombarded with air pollution 150,000 cases of diabetes directly related to air pollution Allerair air filters Molekule (use code BEN) It's possible to begin reversing lung damage from smoking within 12 months Full spectrum antioxidants Taurine Wild plants, herbs and spices [20:32] Hormesis: Things that are bad for you in large amounts can strengthen your body's stress resilience in small amounts Plants have built-in defense mechanisms Xenohormesis Book: The Plant Paradox by Dr. Steven Gundry Plants cause gut damage to those with existing gut damage (leaky gut, dysbiosis, etc.) Book: Eating on the Wild Side by Joe Robinson Avoid processed food [24:45] Two ingredients commonly found on processed "healthy" food: vegetable oil and sugar Two things to track: Glycemic variability w/ Dexcom G6 Inflammation High amount of legumes [28:50] Rinsing and sprouting Legumes are a low glycemic index food Slow carbs A slice of bread can spike your sugar higher than a candy bar Low level physical activity throughout the day [34:50] You don't see cross fit regimens in blue zones Gyms are a product of the post-industrial era Natural way to exercise is walking, chopping wood, outdoor activities Standing work station [link] Treadmill work station [link] Design your lifestyle so that the gym is an option, not a necessity Strenuous gym activity will not improve your longevity Social engagement [38:25] Podcast: The Hidden Health Epidemic Nobody is Talking About It's impossible to simulate face to face interaction in a digital format Use the Internet as a means of facilitating F2F contact, not trying to simulate it (meetup.com) Drink healthy forms of alcohol [40:55] Ben's cocktail: Gin or vodka, on the rocks, wedge of lemon and house bitters FitVine Wine (discount code greenfield10 for 10% off) Podcast: Todd White of Dry Farm Wines Alcohol is toxic, but while too much can be harmful, a little bit can be efficacious Calorie restriction and fasting [44:15] Long time between meals, your body up regulates cellular autophagy (cleanup of cellular debris in your body) Intermittent fasting allows you to derive benefits of fasting without calorie restriction The Longevity Diet by Dr. Valter Longo Ben's fasting protocol: Quarterly 5 day period of calorie restriction Daily intermittent fast Monthly: Dinner to dinner fast Strong life purpose [48:05] Have a reason you exist, a mission statement, you can clearly articulate to yourself and others regardless of your circumstances My podcast with Mastin Kipp Claim Your Power: A 40-Day Journey to Dissolve the Hidden Blocks that Keep You Stuck and Finally Thrive in Your Unique Life's Purpose The Subtle Art of Not Giving a F*ck by Mark Manson Low amounts of stress [50:40] Go for the low hanging fruit (natural stress relief) before using technology Our breath (prana) is a natural stress relief Box breathing Alternate nostril breathing 4-7-8 breathing Spiritual discipline and belief in a higher power [53:12] Believe we're more than blobs floating through the air, seeing who can accumulate the most trophies Physical intimacy [55:30] Nature doesn't want to keep organisms that aren't useful to its propagation Having sex regularly sends a message to Nature that you want to propagate the Earth -Advanced biohacking practices people are using on top of those already mentioned...57:35 Hormesis via hyper oxygenation (hyperbaric chamber) Hormesis via EWOT (exercise with oxygen therapy) Thermogenesis Cryotherapy chamber Full spectrum infrared sauna (Clearlight) UVA/UVB radiation Rhodiola Calorie restriction pneumatics Rapamycin Metformin Ketone esters Insulin stabilizing herbs and spices Ceylon cinnamon Apple cider vinegar Berberine [thorne link] Bitter melon extract Sirtuin activating compounds (stacs) Fisetin Quercetin Stem cells V cells Exosomes Foods that can enhance your own stem cell productioin Colostrum Chlorella Aloe vera Coffee berry fruit extract Ben Greenfield's ultimate anti-aging smoothie Peptides Joint degradation: BPC 157, TB 500 Mitochondria: Humanin, mots-c Thymus Epithalon C Max Mitochondrial support TRU Niagen Pau d'arco bark tea Glutathione Fish oil Telomeres Astragalus Trusii Hydrogen-rich water (enter code BEN at checkout and get 30% off) TA 65 TAM 818 (link?) -And much more... Resources mentioned: - Book: The End of Alzheimer's by Dale Bredesen - Book: Blue Zones by Dan Buettner - Book: The Plant Paradox by Dr. Steven Gundry - Book: Eating on the Wild Side by Joe Robinson - Book: The Longevity Diet by Dr. Valter Longo - My podcast with Mastin Kipp - Book: Claim Your Power: A 40-Day Journey to Dissolve the Hidden Blocks that Keep You Stuck and Finally Thrive in Your Unique Life's Purpose - Book: The Subtle Art of Not Giving a F*ck by Mark Manson - Rhodiola - Ketone esters - Ben Greenfield's ultimate anti-aging smoothie - BPC 157 and TB 500 - Thymus - Epithalon - TRU Niagen - Pau d'arco bark tea - Glutathione - Fish oil - Astragalus - Trusii Hydrogen-rich water (enter code BEN at checkout and get 30% off) - TA 65 - TAM 818 Episode Sponsors: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -Trusii: Contains a host of anti-inflammatory, anti-obesity, and anti-allergy benefits. For this reason, I have decided to now make consumption of hydrogen-rich water an important part of my daily nutritional routine...and I highly recommend it! Enter code: BEN at checkout and get 30% off your order! -Vuori: Activewear and athletic clothing for ultimate performance. Vuori is built to move and sweat in, yet designed with a West Coast aesthetic that transitions effortlessly into everyday life. Receive 25% off your first order when you use discount code: "ben25" -Policy Genius: Whether you're an insurance expert or a newbie, Policygenius created a website that makes it easy for you to compare quotes, get advice, and get covered. Got a question for me about today's podcast? Just leave a comment below and I'll reply!  
01:13:26 6/5/2019
It's cannabis time! The "Kentucky Castle" is a unique destination hotspot with a full biohacking facility, sauna, farm-to-table restaurant, precision medicine arm, hemp farm, horse facilities, and much more. It is owned by one of the physicians who hosts the "Wild Health" podcast, on which I was recently a guest.  Recently, at the castle, I had the pleasure of giving a talk on how to hack your biology and get the most out of the genetics you were born with. Afterward, I took part in a Q&A with several of the physicians in attendance at the conference, which you can also listen to here. But during my time at the castle, I also had a chance to duck away with Dr. Matt Dawson, Dr. Michael Mallin and CBD formulator and researcher Taylor Bright to talk all things cannabis and CBD. We hit record on the mics and recorded the hemp goodness for you on today's episode. In this episode, you'll discover... -The chemical effects of using marijuana... Most often referring to tetrahydrocannabinol (THC) - the part of the cannabis plant that induces the euphoric state THC levels have steadily risen from 3-5% in the 1960's to as high as 28% today THC fits inside the CB1 receptor in the cerebral cortex of your brain (which causes the "high") Less often known is cannabidiol (CBD) It's one of over 80 cannabinoids in the hemp plant It accounts for up to 40% of the plant's total cannabinoid extract CBD is more often researched for medical purposes than THC How CBD and THC is separated Hemp plants are grown with male plants fertilizing female plants Remove the male plants, and the female plants produce THC (they produce very little THC when pollinated by the male plants) Male and female plants together meet the international standard of <1% THC Female plants contain other cannabinols with efficacious health benefits (CBG, CBGA, CBC, CBCA, CBDA) -The effects of ingesting CBD with and without the THC cannabinol... CBD serves as an antagonist to CB receptor agonists (a substance which initiates a physiological response when combined with a receptor) In other words, CBD "mutes" the effects of the CB1 or CB2 receptors CBD can elongate the "high" of THC by inhibiting the cytochrome p450 enzymes Also an antagonist to the GPR55 cannabinol; found in the caudate nucleus section of the brain Because CBD does not attach to the CB1 or CB2 receptors, it's not addictive or habit forming CBD acts as an agonist for the 5-HT 1A receptor (for anti-depressant, anti-anxiety effects) It's an allosteric modulator of your opioid receptors (for pain and chronic inflammation reduction) 2010 Article: Key Ingredient Staves Off Marijuana Memory Loss CBD has strong antioxidant and anti-inflammatory effects U.S. Government took out a patent on the antioxidant properties of cannabis (while officially denying it had any medical benefit) It's almost impossible to overdose on CBD (due to low level of toxicity) -The interesting history of cannabis... 2700 years ago, a Persian teacher named Zoroaster penned a compendium of over 10,000 plants; hemp was at the top Hippocrates also recommended cannabis extracts for their medicinal qualities Ethiopian coptic church used cannabis in a sacrament in AD 45 Sir Russell Reynolds prescribed cannabis for Queen Victoria who was suffering from menstrual cramps The father of French psycho pharmacology, Jean-Jacques Moreau (de Tours), advocated for the use of cannabis Hemp was in high demand during the American revolutionary period Anything that can be made from plastic can be made from hemp -The source of the stigma surrounding the use of CBD... The Boggs Act of 1951 set mandatory sentences for drug users; claimed that cannabis was addictive Voluminous expert testimony to the contrary has been overridden in the court of public opinion by claims that marijuana is a "gateway drug" to more addictive drugs Book: Marihuana Reconsidered by Lester Grinspoon (read for free here) CBD gives nearly the same effect of opioid drugs (such as morphine) without the addictive quality -The effects of CBD on our pathways... Hormonal: Reduces susceptibility to stress in HPA axis The pancreas secretes glucagon and insulin THC increases glucagon levels; CBD lowers insulin levels Lower rates of obesity and Type 2 diabetes among CBD users Has been shown to modulate acute and chronic inflammation CBD is an excellent recovery compound (but not immediately after working out) How it affects insomnia: Cannabidiol activates the same adenosine receptors as caffeine It can enhance or help sleep if caffeine is not present -How to know what CBD product to buy in the current unregulated marketplace... Third party test reports are made available; a company doing things the right way isn't afraid of transparency 3 main ways to extract CBD at the moment: Hydrocarbon (through the use of butane) CO2 (in the super critical form) Ethanol (done cryogenically) Ethanol is Taylor's preferred method for CBD extraction Blended with coconut oil; some oil emulsions for topical use -Ben shares the most common questions asked of him regarding CBD and what is getting the best results... CBD can take some of the edge off of THC, reduce its psychoactivity Decreases cytochrome p450 pathways Most profound use for it is its antioxidant and anti-inflammatory potential Lowers cortisol based on its activity on the HPA axis Sleep, anxiety, stress regulation -Why Taylor prefers the ethanol mode of CBD extraction over the others... It creates a more natural product CO2 is more efficient but pulls out plant waxes and lipids you want to remain in it All ethanol is pulled off the final product via a rotary evaporator Full cannabinoid profile on all products; shows its efficacy in the various strains of CBD -Why precision in dosing and THC:CBD ratios is so important... Dosages are highly individualized It affects different people in different ways (sleep, anxiety, etc.) Studies of the effects of CBD need to take these variants into account Endurance athletes are finding that micro doses of THC with CBD is very helpful Legality issues depending on the event Opioid like effects (dulling the pain) Stress reduction -The specific ways Ben, Mike, Matt and Taylor use CBD... Sleep (when necessary, not all the time) Topical: Muscle spasms and pain, CBD sex lubes, enemas -How a novice or new user should shop for CBD... Resources mentioned in this episode: -The Wild Health CBD discussed in this show (use code Ben10 to get 10% off). They use only pure C8 as the carrier oil and control the process from seed to bottle 100% with our in house team of chemists, farmers, and doctors. -Articles and podcasts on bengreenfieldfitness.com related to CBD -Book: Marihuana Reconsidered by Lester Grinspoon (read for free here) -2010 Article: Key Ingredient Staves Off Marijuana Memory Loss -My podcast with Drs. Dawson and Mallin Episode Sponsors: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -Organifi Green Juice: Now you can get all your healthy superfoods in one glass...with No Shopping, No Blending, No Juicing, and No Cleanup. Get a 20% discount on your entire order when you use discount code: BENG20 -Four Sigmatic: I've been using Four Sigmatic products for awhile now and I'm impressed by the efficacies of their mushroom products. I use them. I like them. I support the mission! Receive 15% off your Four Sigmatic purchase when you use discount code: BENGREENFIELD -MVMT Watches: Clean design, minimal and high quality products. MVMT watches start at just $95 and have sold nearly 2 million watches in over 160 countries. Get 15% off your order PLUS free shipping and free returns when you order through my link. Got a question for me or the guys at the Kentucky Castle about cannabis, CBD, or anything else we talk about in this episode? Leave a comment below and we'll reply!  
01:07:28 5/31/2019
In today's podcast episode, we unpack all things amino acids... "...I had two conditions: an injured hamstring and a burned-up stomach, and I wasn't any closer to getting better. I couldn't explain to myself what had happened, but I filed it away as a reaction that my body had to something it didn't like or couldn't handle. Sometime later, I ran into a friend of mine who had discovered a blend of amino acid tablets while he was in Europe. They were only sold in pharmacies, and were made of pure pharmaceutical-grade ingredients. He said athletes took them and they were excited about their much-reduced healing times and improved strength. Then, he gave me a couple of bottles to try. I am an avid self-experimenter, so I went with it. I had competed in the Ironman World Championships eight times, and my annual goal was to return to the race. I needed fast enough times to qualify, and I'd never get there that year if I didn't get myself healed. I started taking ten of the essential amino acid tablets twice per day, as my friend had instructed. I could tell within a few days that my body liked them. Week by week, I felt stronger and my hamstring pain was going away. After about six weeks, I decided to go to the track and give my leg a real test. Six hard quarter mile repeats later, I walked to my car elated. There was no pain and my legs had their spring back! The optimum protein nutrition of this unique blend of essential amino acids had healed me. I remember thinking, "I believe I've found the solution." In the weeks that followed, I noticed other positive physical changes. My heart rate on a maximum heart rate challenge increased by twelve beats?it went from a stable 174 to 186 without any change in my training methods. It was due to the nutrition. And even though there was no visible difference in my body's appearance, I had gained ten pounds of lean body mass. I could not conceive of how this was possible, so I called the product formulator to discuss the changes I had experienced. He said that after years of inadequate nutrition as a vegetarian, the essential amino acids were filling in lean body mass deficiencies. My bones, liver, and heart now weighed more, and this was why I didn't look any different?my organs and tissues had simply increased in weight. Five months after beginning the amino acids, I achieved a personal best at Ironman Canada, in Penticton B.C. In my new and improved physical state, I began to wonder if my vegetarian, protein- deficient diet was the reason why the anti-cancer enzymes scorched my stomach. Could it be that the mucous lining in my stomach was inadequate, and that had also held back the healing of my hamstring? I very badly wanted to find out, so I decided to try the enzymes again. I followed the full protocol, twelve tablets, six times per day for three consecutive days. I had no adverse reactions, and my stomach was fine. I learned that because my overall body protein levels had normalized, the mucous layer in my stomach was better able to handle the enzymes. What a revelation! I thought, could this also be a key problem with my patients and their various conditions? " Thus begins the new book "The Search For The Perfect Protein", by 42 time Ironman triathlete Dr. David Minkoff. Dr. Minkoff graduated from the University of Wisconsin Medical School in 1974 and was elected to the "Phi Beta Kappa" of medical schools, the prestigious Alpha Omega Alpha Honors Medical Fraternity for very high academic achievement. He then completed both a Pediatric Residency and Fellowship in Infectious Disease at the University of California at San Diego. He worked at the University of California and Children's Hospitals in San Diego as an attending physician in infectious disease while conducting original research on Ribaviron, a broad spectrum anti-viral agent to fight disease. He also co-directed a neo-natal intensive care unit and worked in emergency medicine. In 1995, his wife became ill, and her physicians couldn't find what was wrong. Not accepting their "no hope" conclusion, Dr. Minkoff went on a search to help her that led him out of emergency medicine into complementary and alternative medicine to find the answers. In the process he gained expertise in Biological medicine, heavy metal detoxification, anti-aging medicine, hormone replacement therapy, functional medicine, energy medicine, neural and prolotherapy, homeopathy and optimum nutrition. He studied under the masters in each of these disciplines until he became an expert in his own right. The answers he found were soon in demand when others learned of his wife's return to good health. In response to this, he and his wife, Sue Minkoff RN established Lifeworks Wellness Center in 1997 and it quickly became one of the most comprehensive complementary and alternative medicine clinics in the U.S. The demand for the products and protocols he discovered became a catalyst for founding BodyHealth.Com, a nutrition company that now manufactures and distributes these cutting-edge solutions for the many health problems today. Dr. Minkoff writes two free online newsletters, "The Optimum Health Report" and "The BodyHealth Fitness Newsletter", to help others learn about optimum health and fitness. In my conversation with Dr. Minkoff, you'll learn... -Dr. Minkoff's history with amino acids and why he wrote his new book... The science behind amino acids and protein wasn't keeping up with the commercial PR and marketing Strained a hamstring while running an Ironman triathlon in 1982 Tried everything possible to no avail Tried amino acids and felt no pain, no discomfort Max heart rate rose by 12 bpm Muscle and bone tissue filled in A patient who was familiar with natural cancer treatment recommended a pancreatic enzyme treatment; had very negative results He then supplemented it with essential amino acids and was perfectly fine Saw potential cure for other problems patients may be having (that are not cancer) ION profile with 40 amino acids - Genova Kit He realized that if it was effective for him, it would be beneficial for others He now sees amino acids as an essential element of a workout and proper recovery Vegans and vegetarians are notoriously deficient in aminos, B12, Iron and other nutrients Highly recommend an Amino supplement -About CHYMO, the thyroid and its interaction with amino acids... Chymotrypsin: an enzyme made in the pancreas that is necessary to digest food Actin: the main protein in muscle; Contains 5800 different amino acids in one chain of the muscle fiber Must be broken down into individual amino acids in order for the intestine to absorb it Vicious cycle: amino acids not enough to make chymotrypsin; can't digest protein properly; amino acids can't get into the bloodstream Many people are iodine deficient Also low in tyrosine (made from the essential amino acid phenylalanine) These are common issues -The link between amino acids/proteins and the gut and digestion... The inner lining of the intestine is one cell thick Leaky barrier membranes: your body gets exposed to foreign proteins 70-80% of your immune system is behind the membrane barrier  (Peyer's patches, gut associated lymphoid tissue) Inner lining of the gut has a high turnover (every 3-5 days) due to the exposure, wear and tear, etc. Leakage occurs when these membranes are not replaced Lack of amino acids slows the turnover rate (10-12 days) Endurance training compromises the immune system due to the pounding on the body -How amino acids are used by riders in the Tour de France bike race... Podcast: How Tour de France racers make it through the grueling stages w/ Dr. Jeff Spencer Dr. Spencer is a former Olympic biker who worked for the U.S. team during the Lance Armstrong era Minkoff gave Spencer amino acids to give to the riders during one of the races: After 21 days, athletes are broken down, even with optimal nutrition, medical care, etc. Athletes who used amino acids didn't break down; performance improved Athletes and coaches overwork and don't allow adequate recovery time; results in a broken immune system -Why not derive amino acids from whey protein, spirulina and other sources?... The amount of protein listed on the package doesn't translate to amounts in other sources (fish, steak, spirulina, etc.) Medication to stop stomach acid stops protein digestion Pepsin enzyme which digests protein requires a very acid stomach Cells have two pathways with which to deal with the amino acids: Anabolic: Turns amino acids into the proteins the cell is responsible for (hair, liver, muscle etc.) Catabolic: Nitrogen becomes a waste product; chain leftover looks like a carbohydrate Ratio of essential amino acids in Kion Aminos is very specific; the body will use amino acids into making protein Nitrogen utilization study Spirulina is good for some things; amino acids is not one of them Adding non-essential amino acids decreases the efficacy of the product Collagen has 50% non-essential amino acids -The chemical configurations of amino acids... The body can only use the "left-handed" configuration (L form) Most amino acid forms have very low amino acid utilization because they include the R form -How amino acids work with fasting and/or ketosis... You can take amino acids and not spike blood glucose levels Excessive proteins will kick you out of fasting is a myth Amino acids work very well for fasting in an anabolic state 10 g of amino acids is 4 calories (less than a stick of gum) -How safe amino acids are for children... -And much more... Resources from this episode: - Kion Essential Aminos Acids - Dr. Minkoff's new book "The Search for the Perfect Protein" - Pancreatic enzyme therapy for cancer - ION Profile with 40 Amino Acids - Genova Kit - Diagnostechs Stool Panel - Sanesco Labs HPA Profile - BioSteel - Podcast: Episode #168: How To Banish Chronic Pain Forever. - Podcast: Why You've Been Lied To About Cancer And What You Can Do About It. - Podcast: Amino Acids, BCAA's, EAA's, Ketosis, Bonking & More With 41 Time Ironman Triathlete Dr. David Minkoff. - Podcast: How Tour de France racers make it through the grueling stages w/ Dr. Jeff Spencer Episode Sponsors: -Kion Aminos: Building blocks for muscle recovery, reduced cravings, better cognition, immunity, and more. Get 10% off your order of Kion Aminos, and everything at the Kion site when you use discount code "bgf10" at checkout. -JOOVV: After using the Joovv for close to 2 years, it's the only light therapy device I'd ever recommend. Give it a try: you won't be disappointed. Order using my link and receive a nice bonus gift with your order! -Harry's Razors: Try the shaving company that's fixing shaving. Get a $13 value trial set that comes with everything you need for a close, comfortable shave when you go to harrys.com/greenfield -Birdwell Beach Britches: Quality is our Gimmick isn't just our slogan, it's a commitment we honor with every stitch we sew. 100% money back guarantee. Get 10% off your order, PLUS free shipping on any order over $99 when you use discount code: BENG. Do you have questions, thoughts or feedback for Dr. Minkoff or me? Leave your comments below and one of us will reply!
01:21:54 5/29/2019
I get tons of questions about water. What water filter is best? Should I add minerals to my water? What do you think about alkaline water? Structured water? Hydrogen rich water? Deuterium depleted (DDW) water?  And much more... So on this podcast, I interview one of the world's leading experts on water and a guy who, along with my father Gary Greenfield, has taught me more about water than just about anyone I know. His name is Robert Slovak. Robert is a degreed Mechanical and Aeronautical & Astronautical engineer best known for co-founding Water Factory Systems in the early 1970's. He and his brother were among the early developers of Reverse Osmosis (RO) technology and its many applications. Their successful innovations encompassed home and office RO drinking water systems, bottled water production, laboratory purification, hemodialysis, seawater desalination, microchip production, bottled water production, water vending, spot-free vehicle washing and scores more. As a result of the rapid growth of RO applications, Robert's ongoing seminars and a best-selling industry book on the subject of POU (Point of Use) RO, he became a well-known figure in the water industry. In 1989 Water Factory Systems was purchased by CUNO Inc, a global leader in fluid treatment. Since then, it was acquired by the 3M Corporation, which continues to market many of their original products. Robert officially retired from the US water industry in 1996 and went on to bring his knowledge and experience to Brazil, Asia and other international markets. He put together a team and published Agualatinomerica magazine to establish a legitimate water equipment and education infrastructure in Brazil and South America. His "students" continue to play a major role in Brazil's water industry. In 2004, while in a remote location of Brazil, Robert became seriously ill and was introduced to an obscure 1897 medical discovery known as Original Quinton Marine Plasma (after the famous revolutionary biologist René Quinton). Robert attributes his "jungle" survival to its remarkable healing properties. This ocean-harvested nutraceutical contains the entire Periodic Table of organo-complexed minerals & trace elements as well as essential and rare micronutrients and has been continuously produced for more than a century. Having been an avid student of health and nutrition science for decades, Robert recognized the remarkable history and efficacy of Quinton Marine Plasma in supporting a wide range of the most difficult health conditions and has distributed Quinton Marine Plasma to leading-edge clinics and health practitioners worldwide since 2008. For the past nine years Robert's focus has been on bringing a new nutraceutical breakthrough called "Molecular Hydrogen" (H2) to the medical profession and health-minded consumers. This "smallest molecule in the Universe" has been overlooked for its remarkable health benefits until now. With more than 800 worldwide health studies on the subject, physicians, researchers and clinicians have been proclaiming Molecular Hydrogen (H2) as the most unique and versatile antioxidant and signaling molecule. In 2010 Robert co-developed a practical way for everyone to benefit from this discovery by creating the first reactive hydrogen tablet that infuses water with a supersaturated concentration of molecular hydrogen (H2) gas. This proven nutraceutical is now in its 9th year of distribution in both professional medical and consumer markets. In 2011 Robert became a founding investor in the Quicksilver Scientific Corp. that was developing a groundbreaking new technology to deliver nutrients and nutraceuticals to the cells. It is referred to as nano-encapsulated liposomes. In just a few years, Quicksilver Scientific established its scientific dominance in this growing field and is currently expanding its product scope and global distribution. While attending medical and wellness conferences throughout North America, Robert recognized the persistent minefield of water-related misinformation encountered by doctors, patients and consumers alike - that's after spending nearly 50 years in the water technology industry. This unsettling experience soon turned into the motivation to do something about it and Water & Wellness was established in 2017. A team with more than 150 years of combined experience was assembled to create a product line of advanced Point of Use (POU) and Point of Entry (POE) water treatment systems for health and wellness minded consumers. In addition, a line of synergistic water additives was formulated for the consumer market including Quinton and QuintEssential minerals & trace elements, Active pH Restore alkalizing mineral powder, Active H2 ULTRA molecular H2 tablets and Active Ribose C high-bioavailability vitamin C. Recently, Robert's 25-year interest in Deuterium Depleted Water (DDW) took a new direction forward. With a combination of Soviet-era research from the 1960's and recent announcements explaining the profound physiological benefits of water with reduced Deuterium content, Robert decided to act quickly in making a reliable and affordable supply available in North America. Soon, health practitioners and health-minded consumers will be able to obtain the most deuterium depleted Litewater brand DDW through soon-to-be-announced channels nationwide. Robert continues to be a very active international figure in the rapidly expanding water technology, wellness and anti-aging community, making appearances and presentations worldwide. During our discussion, you'll discover: -Why and how Robert went from the aerospace industry into the water industry... Robert and his brother Jack were both working in the military industrial complex and were just plain bored to tears They became aware of a new technology called membrane separation, aka reverse osmosis They were pioneers in water systems in homes and restaurants, to micro electronics manufacturing Built the first hemodialysis system (portable dialysis) Didn't invent reverse osmosis, but refined and developed products that used it (the spot-free rinse being the most famous) -How a near-death experience made Robert aware of a forgotten scientific discovery that led to his current work... In 2004, Robert came down with gastroenteritis after moving to Brazil in retirement Was given by a local man 6 vials of quinton marine plasma, a harvested extract of plankton from the ocean This is what they used in the absence of proper health care in that area Was first discovered in 1897 Percutaneous Hydrotomy: a protocol used to treat serious conditions such as a damaged spine Not to be used as a supplement of injectable for general wellness Super hydrating a specific location with sea water Plankton bloom: one of the most complex bioreactors Make about 65% of the oxygen on earth Heavily protected by national and international governing bodies Robert's brother and business partner passed away in 2016; passed on the license to Quinton to Quicksilver Scientific Water and Wellness -The secrets to Robert's youthful physical appearance... Quinton Moderate exercise Grounded with the earth Strict paleo dietary regimen (see below for details) Trace elements (from the Quinton) 40+ supplements taken daily (see below for details) -How to set up the ideal water filtration system in your home... Always find out what exactly is in your water (EPA water quality report for local water company) Filtration system, temperature, etc. all matter in the quality Two methods for removing the greatest number of contaminants: Distillation + activated carbon Reverse osmosis + activated carbon Then remineralize the water (quinton, trace liquid minerals, Celtic sea salt) Why Celtic sea salt, and not another type of sea salt? Jacques DeLangre (founder of Celtic) was a student of Rene Quinton himself Celtic is not rinsed. When you rinse salt, you rinse away 30-40 trace elements Himalayan sea salt is an underground salt mine; has iron oxide contamination The best water filtration systems on the market: AquaTru water filter AquaTru minerals Sanitize the storage tank minimum once a year, and every time you change filters Incubators for huge levels of bacteria SteriPen portable water purifier WoW (Water on Water) under the counter filtration system LED and UV sterilization is coming soon -Robert's take on alkaline water... He's against it; has been for 7+ years It's "the scientific misconception that became a multi-billion dollar business" The engineer who conceived of it didn't know the distinction between "alkaline" and "alkalinity" Another misconception in how "ph" levels affect acid in the water Match vs. fireplace: which will heat your home? Once you drink alkaline water, the body will change the ph level dramatically Alkalinity comes from adding trace minerals which have a buffering capacity: carbonates and bicarbonates Fresh green juices are a great way to alkalize the body (no ph levels) PRAL (Potential Renal Acid Load) Chart -Robert's take on structured water... Refers to the molecular configurations the water molecules take on that are purported to have some physiological significance These arrangements are very fickle; they change every second It fails when you drink it; no structuring can survive the stomach (remember, it can dissolve a steak) There have been no studies that show consistent physiological benefits The only structuring Robert would consider is vortexing -And what about hydrogen-enriched water?... Robert created the very first hydrogen reacting tablet in 2010 Not to be confused with hydride ions (which Robert erroneously did from the outset) Tyler LeBaron (listen to my podcast with him) set the record straight You can combine Quinton minerals with h2 tablets -What is deuterium, and what is deuterium-depleted water... The hydrogen in water consists of 3 isotopes: protium, deuterium, tritium (which is of little consequence) Deuterium is twice as heavy as protium (the only isotope that has that large a disparity with its sister isotope) Water is actually 3 different molecules: H2O, HdO, and D2O There are 150 deuteriums for every 1 million protiums in water When water is made with deuterium, it's called "heavy water" (it's used to power nuclear power facilities and make nuclear bombs) America won the race to extract the deuterium from regular water during World War 2 Unusual biological effects of deuterium-depleted water on plants and animals: Increases in life span, Growth rates, Survival and diseases Russian scientists reported this, they were not taken seriously by the global scientific community Many variations or levels in which deuterium can be removed from water and still be considered "depleted" Incredibly complicated process of removing deuterium from water A camel produces deuterium-depleted water naturally; it's why they can survive without water for weeks in the desert -And much more! Resources from this episode: - Robert Slovak's "Water & Wellness" website (use code GREENFIELD to save 10%) - AquaTru water filter - Podcast: The Genius Mad Scientist Who Invented The Very First Fitness Product Ben Ever Bought - Along With "The Best Water Filtration System That Exists" & Much More. - Trusii Hydrogen Rich Water (use code BEN for 15% off + free shipping) - Quinton minerals by Quicksilver Scientific (use GREENFIELD10 to get a discount) - Percutaneous hydrotomy - Zach Bush's Nitric Oxide Dump - AquaTru minerals - Celtic Salt - Steripen UV Water Purifier - PRAL (Potential Renal Acid Load) Chart - Greenfield Naturals Structured Water filter - My interview on hydrogen-rich water with Tyler Lebaron - SteriPen portable water purifier - Robert's 14 ingredient "Bulletproof Coffee Recipe" (for 3-4 cups): - 450 ml boiling-hot water - 3 small cups of organic espresso coffee - 1 tbsp grass-fed butter  (use code GREENFIELD for 15% discount storewide. Offer good for up to 2 orders per customer. Excludes orders over 40 lbs, sale items, volume discounts, and gift certificates) - 1 fl. oz. coconut creamer - 2 tablespoons organic MCT oil  (use code BEN for 10% discount) - 1 tbsp virgin coconut oil - 1 scoop collagen peptide powder - 1 scoop whey protein powder - 1 heaping tsp cacao powder - 1 heaping tsp turmeric powder - 1 tsp Ceylon cinnamon - 1 tsp MSM powder - 1/2 tsp Magnesium L-threonate - 1 scoop Active pH Restore (alkalinity powder) - 1 scoop Active C with Ribose (Vitamin C powder) - 1 vial QuintEssential 3.3 (minerals & trace elements) - The supplements Robert takes: Robert's Life Extension List: - LEF Mix capsules - Vitamin D3 5000IU - Health Booster - Super Omega-3  - Mega Lycopene  - Advanced Bio-Curcumin  - Cognitex w/ Pregnenolone & Brainshield  - Skin Restoring Phytoceramides 30 caps  - Optimized Folate  - Ultra Natural Prostate  - Cardio Peak  - Brite Eyes III  - Macugard Ocular Support w/Astaxanthin  - Super Miraforte  - Endothelial Defense  - PQQ Caps  - Super Ubiqunol CoQ10  - Triple Action Cruciferous  - AMPK Activator  - Milk Thistle  - NAD+ Cell Regenerator  - Super Selenium Complex  - Neuro-Mag Threonate  - Super Carnosine  - Acetyl L-Carnitine Arginate - DMAE Bitartrate - Mega Green Tea Extract  - DHEA Complete  - Vinpocetine  - Arterial Protect  - D-Ribose powder  - SAMe  Robert's Water & Wellness List: - Quinton Hypertonic (or QuintEssential) (use code GREENFIELD to save 10%) - Active Ribose C  (use code GREENFIELD to save 10%) - Active pH Restore  (use code GREENFIELD to save 10%) - Active H2 ULTRA  (use code GREENFIELD to save 10%) - Ageless Defense  (use code GREENFIELD to save 10%) Other Supplements Robert takes: - Tri-Iodine - MSM Powder - Mega Strength Beta Sitosterol - Wobenzym - C3 Complex Turmeric Curcumin - Multi-Fiber Colon Cleanse - Mushroom Extracts  (use code BENGREENFIELD for a 15% discount) - MCT Oil (use code BEN for 10% discount) & Coconut Oil Episode Sponsors: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. -Organifi Red Juice: Enjoy all the benefits of the 11 superfoods and their micronutrients that help increase resting metabolism, support cardiovascular health, and remove toxins to turn back the hands of time! Receive a 20% discount on your entire order when you use discount code: "BENG20" -Thrive Market: Organic brands you love, for less. Your favorite organic food and products. Fast and free shipping to your doorstep. Receive 25% off your order when you use my link! -FitVine Wine: Don't let the word "less" fool you. FitVine wines offer rich flavor profiles and the alcohol content (13.4 - 13.9% alcohol) you'd expect from a fine wine. Use discount code: GREENFIELD10 for 10% off your order. Do you have questions, thoughts or feedback for Robert or me? Leave your comments below and one of us will reply!  
01:17:25 5/24/2019
You've no doubt heard of controversial "young blood transfers", made popular of late in the anti-aging and longevity industry by articles such as: -Questionable "Young Blood" Transfusions Offered in U.S. as Anti-Aging Remedy -New Yorkers will soon be able to have the blood of 16- to 25-year-olds transfused into their body. But does it actually do anything?  -Startups Flock to Turn Young Blood Into an Elixir of Youth But what has completely flown under the radar is the fact that plasma transfusions of young blood have been found in clinical research studies to have never-before-seen effects on chronic health conditions such as Alzheimer's, Parkinson's, autoimmunity and many others.  In today's podcast, with Mark Urdahl and his lead nurse Gloria, you'll get never-before-heard breakthrough information on how young blood transfusions really work for these conditions, along with their true effects on anti-aging and longevity. Mark Urdahl, one of my guests on this podcast, serves as Chairman and CEO of the Young Blood Institute, a non-profit corporation conducting clinical trials in the use of therapeutic plasma exchange as a modality to systemically prevent cellular senescence and the onset of associated immunological, neurological, and cardiovascular disorders. Mr. Urdahl and his team at the Young Blood Institute have also pioneered the concurrent use of the world's most advanced, state-of-the-art, ultrasensitive, high-precision blood serum measurement technologies to capture comprehensive "big data" of the human body, an unprecedented combination of testing technologies in human medicine or human clinical research, in order to understand never-before-seen correlations which might lead to discovery of root causes of age-associated disorders. He began his career with IBM Biomedical Systems, which, in partnership with the National Cancer Institute, invented the world's first automated blood cell separator, first commercially produced by IBM in the 70's as the IBM 2997. After IBM sold its Biomedical Systems business unit to COBE Laboratories in 1984, Mr. Urdahl became a systems engineer supporting IBM large systems accounts, including notable innovators in health care management. Mr. Urdahl went on to lead a distinguished career at IBM, where he held management positions in marketing and sales, technology development, corporate development. After IBM, he founded Applied Science Fiction (ASF), a digital imaging company where he served as Chairman and CEO, overseeing the development of over 150 patent applications and licensing its technology to nearly every major imaging OEM worldwide, including Nikon, Agfa, Minolta, and many others. Mr. Urdahl subsequently formed the Young Blood Institute as a non-profit 501 (c) (3) corporation to research anti-aging therapies under clinical trials, recruiting world-class principal investigators, establishing a nation-wide network of nurses and private care physicians, creating the most advanced biomarker testing platform in the world, and developing a "big data" database capable of storing data in the cloud in perpetuity. In 2008 Mr. Urdahl led an investment group to acquire the storage network monitoring business unit of Finisar Corp, including a portfolio of 20+ patents/applications, to form a privately held company, Virtual Instruments. He subsequently formed the Young Blood Institute to research anti-aging therapies under clinical trials, recruiting world-class principal investigators, establishing a nation-wide network of nurses and private care physicians, creating the most advanced biomarker testing platform in the world, and developing a "big data" database capable of storing data in the cloud in perpetuity. During our discussion, you'll discover: -The history of the world's first blood cell separator... Invented by George Judson in 1965 after his son was diagnosed with leukemia Blood cells were separated manually; very laborious IBM funded this research and many other inventions that have benefited humanity Taber's Medical Encyclopedia -What is blood cell separation and exchange?... Similar to a PRP draw Blood drawn from one arm; spun around in centrifuge; separates red, white, plasma (by gravity); Machine can draw whichever component you want (platelets, plasma, red cells, etc.) Blood is reinserted into the arm sans whichever component you want (ex. plasma) and new plasma is inserted via IV New plasma comes from various sources: actual plasma and purified plasma components Broke college kids donate plasma for gas money (creating a very large plasma pool) Water is taken out of the plasma; what's left is albumin, immunoglobulins, fibrinogen Similar to frozen lemonade (just add water) -How Mark became interested in the transfer of young blood... Was involved in several high-tech yet unfulfilling tasks; desired to do more for humanity Heterochronic parabiosis: the joining of two mice together, one old, one young Systemic milieu Findings of mouse research: There was one solution (young blood) to multiple problems; however, each problem had its own funding, infrastructure, bureaucracy, etc. Both parties are affected: younger deteriorate; older improve Initial goal: reboot the immune system for people over the age of 50 -Why the Young Blood Institute operates as a non-profit organization... Humanitarian research No proprietary issues such as IP, Much learning that yet needs to occur For profit companies naturally focus on profit; Can be contradictory to the idea of research and discovery Takes years for truths to emerge (because of investors, stock, etc.) -The philosophy behind the research and work at the Young Blood Institute... Janko Nikolich-?ugich - The immunobiologist at the YBI Valid clinical evidence requires data How do you prove you've prevented something? By proving it existed in the first place Anecdotal data suggests the effects of plasmapheresis extends beyond the indication that is being treated Cast a wide net, gather as much data as possible (treat the whole elephant) What biomarkers are being tracked: Standardized patient care physical exams Muscle biopsies Muscle function Neurological/cognitive function Many more All tests done before the young blood transfer Not trying to cure; trying to prevent Don't test for telomeres because it's testing whole blood Each cell subset has different telomere lengths Wide disparity in test results Cells are aware of changes in environment, not calendar times -A dramatic real-life example of 2 70-year old Youngblood Institute patients... The plasma that was withdrawn was rather putrid looking After 2-3 treatments (removing old plasma, injecting young plasma) the plasma condition normalized Getting rid of the old plasma really matters Decrease in whole blood viscosity Low shear viscosity: "stickiness" of the blood -What is "big data of the body"?... Digital biomarkers: Apple Watch, HRV, sleep cycles, etc. Unprecedented ensemble of data assembled in one place Correlations (meta data) Data is mined over time -The government's intervention in this type of technology... FDA shut down a for-profit company in the field Mark supports the FDA's action and caution Infusions are additive; can cause circulatory overload YBI does a transfusion; blood volume stays constant Mark doesn't fear an FDA shutdown of the Youngblood Institute because they are in agreement with and support their actions -How something called a "neuro protocol" may lead to breakthroughs in the treatment of Alzheimers... Article: Plasma exchange for Alzheimer's disease Management by Albumin Replacement (AMBAR) trial: Study design and progress An extension of current protocol: 6 treatments over a 6 week period Add a partial monthly treatment for 12 months Mark's lead nurse, Gloria, was the lead on the AMBAR study, and had shocking stories to tell Could potentially lead to treatment of Parkinson's and ALS 60% success in arresting the development of Alzheimers The End of Alzheimer's by Dr. Dale Bredesen Proper clinical trial: unbiased investigators who look at data, not the subjects -The role of a head nurse in a plasma transfusion... It's largely a nurse's procedure Top 6 nurses at the YBI have 230+ years of experience Get lead physicians observations; head nurse will sometimes provide that for them Interact with patients and get their observations Alzheimers affects the family of the patient more than the patient (due to their loss of memory) -Gloria's observations treating patients, both with the AMBAR study and at the YBI... "Early results on Parkinson's and ALS patients are very encouraging" Grifols did a placebo test on patients: Patients already had minimum mild level of Alzheimers "Sham" is used in the best possible sense Patients perceived they were receiving the treatment when they were not Treated over 180 subjects over a four year period One patient in particular deteriorated rapidly while on the sham study "Predictive biomarkers" are used to admit patients into the YBI treatments Some of the good stories: Orchard farmer in his 80's showed remarkable improvement after approx. 8 months (18 treatments) Woman who just turned 60, lost her joy for life; after 2 months, daughter reported amazing progress; flirting with everyone after 5 months Patients regain previously lost memories -Can apheresis be used as an anti-aging treatment even if one doesn't have Alzheimers?... "Apparent health" can be a misnomer; all of a sudden someone can have 3 major diseases YBI doesn't treat patients as young as 30 years old Alzheimers, Parkinson's, ALS symptoms begin very young -Why these studies and treatments are still occurring more or less behind the scenes... -And much more... Resources from this episode: -The Young Blood Institute -The End of Alzheimer's book by Dr. Dale Bredesen -My first interview with Dr. Matt Cook -My second interview with Dr. Matt Cook -Biohacking Alzheimers, Age Reversal, Young Blood, Stem Cells, Exosomes  podcast -My podcast with Tom Ingoglia of the NAD injection clinic in San Diego -Grifols demonstrates a significant reduction (61%) in the progression of moderate Alzheimer's disease using its AMBAR treatment protocol -Taber's Medical Encyclopedia -Article: Plasma exchange for Alzheimer's disease Management by Albumin Replacement (AMBAR) trial: Study design and progress Episode Sponsors: -Kion: My personal playground for new supplement formulations. Ben Greenfield Fitness listeners receive a 10% discount off your entire order when you use discount code: BGF10. Check out the Memorial Day specials and save today! -Trusii: Contains a host of anti-inflammatory, anti-obesity, and anti-allergy benefits. For this reason, I have decided to now make consumption of hydrogen-rich water an important part of my daily nutritional routine...and I highly recommend it! Enter code: BEN at checkout and get 30% off your order. -Pura Thrive: Combines pure ingredients in targeted dosages through a superior delivery mechanism that is unrivaled by any other supplement on the market today. Get 15% off a bottle of the Keto Balance when you go to this link. -Birdwell Beach Britches: Quality is our Gimmick isn't just our slogan, it's a commitment we honor with every stitch we sew. 100% money back guarantee. Get 10% off your order, PLUS free shipping on any order over $99 when you use discount code: BENG. Do you have questions, thoughts or feedback for Mark, Gloria or me? Leave your comments below and one of us will reply!  
01:35:00 5/22/2019

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